Introduction of Ursolic acid

Ursolic acid -- --  loquat leaf extract; English name: Ursolic acid. Ursolic acid, also known as: ursolic acid WuSu acid, ursolic acid is a kind of triterpene compounds exist in the natural plant and it has the cancer resistance, resistance to promote cancer, induced F9 teratoma cell differentiation and anti-angiogenesis effect, is likely to be low toxicity and efficient new anti-cancer drugs. Pharmacological effects: triterpene compounds. Has a sedative, anti-inflammatory, antibacterial, anti diabetes, fight ulcer, reduce blood sugar and so on the many kinds of biological effects.

In addition, ursolic acid has obvious antioxidant functions, and therefore is widely used as a pharmaceutical and cosmetic ingredients. Direction: ursolic acid can significantly inhibit the HL 60 cell proliferation, can induce its apoptosis; Can make the macrophage phagocytosis of mice increased significantly. In vivo tests proved that ursolic acid can significantly boost the body's immune function.

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From:Natural herbal extracts

Atovaquone - d4 pharmacology is introduced

Atovaquone - d4 for hydroxyl 1, 4 - naphthalene, quinoline, is the homologue of the coenzyme Q is the activity of several kinds of parasite. On plasmodium, the role of parts for cytochrome BCL point (point Ⅲ). Atovaquone - d4 reversibility and can combine with peptides on 11500 da molecular group. Dihydrogen orotic acid dehydrogenase is important enzymes in the biosynthesis of pyridine, through coenzyme Q connecting mitochondrial electron transport, hence Atovaquone - d4 by inhibiting the electron transfer to prevent the synthesis of pyridine. Some metabolic enzymes through coenzyme Q in the mitochondrial electron transport, therefore, Atovaquone - d4 inhibitory effect of electron transfer is actually inhibits the activity of these enzymes.

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From:Natural herbal extracts

Hydromorphone related applications

Hydromorphone, a added accepted analogue for dihydromorphinone (not to be abashed by Dihydromorphine, which is a altered acquired of the morphine family), frequently a hydrochloride (brand names Palladone, Dilaudid, and abundant others) is a actual almighty centrally acting analgesic biologic of the opioid class. It is a acquired of morphine; to be specific, a hydrogenated ketone thereof, and it can be said that hydromorphone is to morphine as hydrocodone is to codeine and, therefore, a semi-synthetic drug. It is, in medical terms, an opioid analgesic and, in acknowledged terms, a narcotic. Hydromorphone is frequently acclimated in the hospital setting, mostly intravenously (IV) because its bioavailability orally, rectally, and intranasally is actual low. Sublingual administering is usually above to burning for bioavailability and effects.
Hydromorphone is abundant added acrid in baptize than morphine and accordingly hydromorphone solutions can be produced to bear the biologic in a abate aggregate of water.
Very baby quantities of hydromorphone are detected in assays of opium on attenuate occasions; it appears to be produced by the bulb beneath affairs and by processes which are not accepted at this time and may cover the activity of bacteria. A agnate action and/or added metabolic processes in the bulb may actual able-bodied be amenable for the actual low quantities of hydrocodone aswell begin on attenuate occasions in opium and alkaloid mixtures acquired therefrom; dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly added derivatives of morphine and/or hydromorphone aswell are begin in trace amounts in opium.


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From:Natural herbal extracts

The basic information of the Repertaxin

CAS no. : 266359-83-5

English name: Repertaxin

English synonyms: Reparixin; Repertaxin

Chinese name:

English synonyms:

CBNumber: CB82628350

Molecular formula:

Molecular weight: 0

MOL File: MOL File

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From:Natural herbal extracts

Information of Lovastatin

Lovastatin is a new kind of adjusting blood fat drug listed in the eighty s, because of its unique curative effect, has been hailed as a milestone in the treatment of cardiovascular system diseases, was welcomed by the majority of patients.

This product competitively inhibit cholesterol synthesis in the body, the speed limit in the process of enzyme hydroxyl methyl glutaric acyl coenzyme A reductase, reduce cholesterol synthesis, also increase the low density lipoprotein receptor synthesis, the main working part in the liver, the result of blood cholesterol and LDL cholesterol levels, thus to atherosclerosis and coronary heart disease prevention and control work. This product also reduce blood serum triglyceride level and increase high density lipoprotein level. In mice, for 3-4 times people dose can cause cancer, but not in large-scale long-term clinical trials in humans, increased tumorigenesis. Mutation of the existing research did not find this product to have.

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From:Natural herbal extracts

Losartan drug ingredients

Losartan ( Cozaar ) ( English name : Losartan; Alias: Cozaar Losartan , Losartan ) Method : 1 - butyl-4 - chloro- 5 - (hydroxymethyl) imidazole and sodium methoxide in methanol the reaction solution was stirred , and then the resulting sodium salt and 4' - bromomethyl-2 - cyano- biphenyl in dimethyl formamide was stirred , the ether of the compound obtained , and then sodium azide and ammonium chloride -containing dimethyl formamide reaction, the acid hydrolysis of losartan . Purpose: Cozaar first listed in 1994 , is now in 93 countries have been approved for use for the treatment of hypertension . Oral non-peptide angiotensin Ⅱ receptor antagonist. Mainly used for essential hypertension . Cozaar is the first angiotensin Ⅱ receptor antagonist (AIIA) classes of antihypertensive drugs . Properties: light yellow solid , mp 183.5 ~ 184.5 ℃.
Pharmaceutical ingredients : endogenous renin - angiotensin system (RAS) activation of renin release by the kidneys . Renin from the liver can break down a protein called angiotensinogen , angiotensin decomposed product is I. Although angiotensin I itself has no biological activity, but it is a precursor of angiotensin II , and angiotensin II on vascular , cardiac and other body tissue with a series of biological activity. AIIA drugs such as Cozaar can block the angiotensin receptor (AT1), to avoid binding to receptors of angiotensin II , and ultimately achieve the purpose of preventing vasoconstriction .
Cozaar once a day , usually a dose of 50mg. Similar products Cozaar and Hyzaar is a small dose of diuretic ( hydrochlorothiazide ) combinations , also used to treat high blood pressure. Cozaar treatment alone can not properly control blood pressure in patients can try to use Hyzaar ( losartan 50mg / Hydrochlorothiazide 12.5mg) treatment.
Compared with other anti- hypertensive drugs , Cozaar and Hyzaar main advantage is its well tolerated , side effects is low.


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From:Natural herbal extracts

MatrixylAcetate (Palmitoyl Pentapeptide) The role of the skin

The role of peptide cream ingredients:
1, supple and smooth texture, quickly absorbed, forming skin lock water network;
2, the micro-molecular hydrolyzed collagen and palmitoyl pentapeptide binding, can promote the skin's own collagen production, the real bottom activate the skin from the muscle to the skin of energy;
3, there are a variety of moisturizing ingredients added anti Brightening essence, the real effective repair firm skin while improving skin's dull, long-lasting skin firming Xi stepped lip care.

Eye Hydra Decryption:
Micro-hydrolyzed collagen molecules with a variety of soothing moisturizing ingredients, eye skin instantly inject a large amount of collagen and moisturizing elements that promote eye skin metabolism, can significantly relieve eye fatigue, dry ..... palmitoyl pentapeptide, will enhance the hydrolysis the efficacy of collagen molecules, truly can promote the skin's own collagen formation, to delay the fine lines have a significant effect.



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What is Fresh cheese?

Fresh cheese is a natural cheese category , also known as "fresh cheese ", " fresh cheese " is all other types of natural cheese foundation.
Fresh cheese is a fresh cheese has not been proven , it is sufficient water , sour refreshing taste fresh , low fat content . The most famous is the fresh cheese made ​​from cream cheese if the cream .
Fresh cheese popular in Europe . French-made white cheese (Fromage Frais) as white as its name , and there is a unique fragrance and taste of milk .
Italian production of mozzarella cheese (Mozzarella) was President of Spain, praised as " delicious masterpiece " and its fresh taste best suited as meals eaten directly. Mozzarella processing very elegant, used for pizza is also very good .
The world -renowned French-made fresh cheese with white cheese (Fromage Frais), (St Moret), Bulu Xi Cheese (Boursin), made ​​in Italy Rui Keta Cheese (Ricotta), Muscat Capone cheese (Mascarpone), mozzarella cheese (Mozzarella), Denmark produced DOFO cream cheese (DOFO Cream), feta cheese (Denmark Feta), global production of cottage cheese (Cottage Cheese) and so on.



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From:Food bacteria

The clinical significance of Estradiol

Estradiol transdermal estrogen therapy agent. Supplementary female ovarian secretion of 17-β estradiol deficiency , while avoiding the side effects caused due to oral ( breast pain , weight gain , high blood pressure , gallstones and liver dysfunction , etc. ) . Estrogen can induce cells to synthesize DNA, RNA and associated proteins found in the various tissues .

Clinical significance :
1 . Increase seen in female precocious puberty, gynecomastia , pregnancy ( especially in twins or multiple births ) , tumor secretion of estrogen , ovulation drugs ( such as chlorine Griffin ) , the feminization of men , ovarian tumors, anovulatory dysfunctional uterine bleeding and liver cirrhosis and so on.
2 . Reduction seen in ovarian cancer, mole, intrauterine fetal death , pregnancy-induced hypertension syndrome , hypothalamic tumors, pituitary function of reduced ovarian dysfunction , oophorectomy , delayed puberty , primary and secondary amenorrhea , menopause , oral contraceptive medicine. [ 2 ]
3 , estradiol values ​​increased pathological cause a ) ovarian disorders : ovarian granulosa cell tumor , ovarian germ tumors , ovarian fat-like cell tumors , tumors and other sex hormones , ovarian function showed hyperactivity , increased secretion of estradiol . 2 ) Heart disease: myocardial infarction, angina , coronary artery stenosis. 3 ) Other: systemic lupus erythematosus , cirrhosis, male obesity.
4 , estradiol reduces pathological cause a ) ovarian disease : ovarian agenesis or hypoplasia , primary ovarian failure , ovarian cysts. 2 ) pituitary amenorrhea or infertility. 3 ) Other: A low- or hyperthyroidism, Cushing's syndrome, Addison's disease , cancer, a wide range of infections, renal dysfunction , brain and pituitary of focal lesions , etc., can make plasma estradiol reduce alcohol


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From:Herbal extract