Sunday, April 9, 2017

What is the Iloprost

Iloprost is in front of the similar material, the inhibitor preparation for platelet activation, inhibit platelet aggregation and thrombosis is weakening. This medicine can be through the platelet receptor activation of adenylate cyclase, influence of phosphate ester enzyme activity and cell SAP calcium concentration, reduce the peripheral vascular resistance, mean arterial pressure, and increased heart rate, cardiac index and renal blood flow, promotes urinary sodium excretion. In addition, this drug has protect cells, cardiac function and anti-arrhythmic effects. According to the data reported abroad, this drug is compared with the front ring element, chemistry and biology stability is higher, can produce similar or greater antiplatelet effects. The mechanism of this drug antiplatelet characterized by activation of adenylate cyclase, thereby increasing intracellular adenosine cyclophosphate (cAMP) level, it was reported that this medicine increases the role of intracellular cAMP is top 10 times. In addition, for patients with type 2 diabetes with peripheral artery occlusion, input within this medicine can reduce the plasma fibrinolytic enzyme original activator inhibitor 1 (PAI 1) activity. PAI - 1 type can make the organization fibrin dissolve enzyme activator and urokinase type plasma, the original activator inactivation, is a kind of powerful fibrinolysis enzyme inhibitors.
Warm reminder: often have fever and headache, followed by gastrointestinal reaction, such as nausea, vomiting, abdominal pain and diarrhea. The adverse reaction of the individual difference is very big, but are related to the dose. After drug withdrawal, it quickly alleviate adverse reactions.

What is the Etomidate

Etomidate, attending functions, induction of general anesthesia (short-term anesthesia and pain relievers used).
Etomidate is a kind of hypnotic intravenous anesthetics, imidazoles derivatives, security, is one of commonly used drug anesthesia induction, etomidate has a history of 30 years of clinical application. Etomidate intravenous sedatives, is not the barbiturates are hydroxyl of imidazole salt, its structural formula as shown in the figure below, the formula for C14H16N2O2, molecular weight of 244.29. Etomidate insoluble in water, not stable in neutral solution.
Guidance: the pharmacological characteristics of etomidate is one of the important basis and clinical application of foundation: etomidate has sedative and hypnotic and forgotten, but no pain and muscle relaxant effect, is an important drug combination of general anesthesia sedatives. Etomidate effect is rapid, the body has a rapid metabolism and clear, CSHT study suggests after continuous infusion has no obvious accumulation in the body; Etomidate slightly to cycle suppression is its outstanding advantages, etomidate for breathing is affected, at the same time of reducing cerebral metabolic rate can reduce intracranial pressure, does not affect the cerebral perfusion pressure, etomidate emulsion injection can significantly reduce the pain and adverse reactions such as vascular injury, both for the clinical application provides a good background.

Friday, April 7, 2017

Chemical properties of titanium

Titanium is a chemical element, chemical symbol Ti and atomic number 22, in the chemical elements in the periodic table is located in the fourth period, the first IVB clan. Transition metal is a silvery white, is characterized by light weight, high strength, with a metallic luster, wet chlorine corrosion resistance. Titanium but cannot be applied to dry chlorine, even the temperature below 0 ℃ dry chlorine gas, also can produce severe chemical reaction, generate titanium tetrachloride, more decomposition generated titanium dichloride, even burning. Only when the water content in chlorine gas is higher than 0.5%, titanium to maintain reliable stability in it.
Titanium is regarded as a kind of rare metal, this is due to the existence of decentralized in nature and difficult to extract. But their relative abundance of (among) all the elements in the tenth. Titanium ores are ilmenite and rutile, widespread in the earth's crust and lithosphere. Titanium also exists in almost all organisms, rock, water and soil. Extracted from the main ore titanium need kroll process or method of hunter. Titanium is one of the most common compounds titanium dioxide, can be used to make white paint. Other compounds include titanium tetrachloride (TiCl4) (for catalyst and used in the manufacture of a smokescreen for air cover) and titanium trichloride (TiCl3) (used in catalytic polypropylene production).

What is the stainless steel powder

Stainless steel powder particle shape, good corrosion resistance and durability, its flake particle can be parallel to the coating surface orientation and distribution in the whole film, forming excellent hiding power of shielding layer, blocked the moisture.
By low carbon steel stainless steel powder, chromium containing 18% ~ 20%, 10% ~ 12% nickel, molybdenum, about 3% of the stainless steel as raw material, after atomization in the presence of lubricants (stearic acid) ball grinding and sieving classification made paint, may also directly to the wet ball mill.
Stainless steel powder is mainly used for maintenance coating, heat resistance and durability of paint, stainless steel flake pigments in decorative paint can be extremely attractive natural metal color.

What is the Osmium

Osmium sixth cycle is the periodic table Ⅷ elements, the family member of platinum group metals. Symbol for the Os, atomic number 76, atomic weight of 190.2. Heavy platinum group metals, is one of the largest metal known density.
Osmium exist in osmiridium ore. Will contain the osmium solid roasting in the air, the volatilization of osmium tetroxide by using alcohol absorption, alkali solution after osmic acid salt with hydrogen reduction made osmium metal. Can be used to manufacture high hardness of the alloy. Osmium with rhodium, ruthenium, iridium, or platinum alloy, commonly used as a record player, fountain pen, and bearing in clocks and watches.
Osmium metal elemental medium density is known, its density is 22.59 g/cm3, melting point 3045 ℃, boiling point at above 5300 ℃. The six-party dense lattice. Grey metallic blue, qualitative hard and brittle, in iron dao in a mortar, can easily become powder, osmium powder is blue-black, and osmium metal powder can be spontaneous combustion.
Warm reminder: osmium vapor to be toxic will strongly stimulate the eye mucous membrane, serious can cause blindness.

What are the role of Rubitecan

Rubitecan, about one and a half for the synthesis of camptothecin derivatives, human trials have confirmed that its effective for the vast majority of solid tumor and leukemia, can be oral, centerless, lung, liver, kidney, and nerve toxicity, so it was regarded as the second generation of topoisomerase inhibitors.
Rubitecan for health purposes:
Rubitecan for kang for antitumor medicine
Rubitecan for kang maximum tolerance dose of 1.5 mg/m2 for a long time, under the dose, the main side effect was only mild bone marrow suppression and cystitis, etc., and drug withdrawal and dose reduction can be reversed. The clinical indications for pancreatic cancer, breast cancer and other solid tumor and chronic disease of the bone marrow cells white.

The physiological functions of lactic acid bacteria have

The physiological functions of lactic acid bacteria have? A lot of people for this may not be very understand, here is introduced:
1. The prevention and control of some species commonly suffer from lactose intolerance (when drinking milk of abdominal distention, diarrhea and other symptoms).
2. Promote protein, monosaccharide and the absorption of calcium, magnesium and other nutrients, produce a lot of useful material such as vitamin B group.
3. Increase of beneficial bacteria in the intestine, and improve human gastrointestinal function, restore human intestinal flora balance, form the antibacterial biological barrier, safeguard human health.
4, curb corruption breeding, eliminate corruption bacteria produce toxins, remove intestinal garbage.
5. Inhibition of cholesterol absorption, fall hematic fat, fall blood pressure.
6. The immune regulation, enhance immunity and resistance.
7. Anti-tumor, cancer prevention role.
8. To improve the SOD enzyme activity, eliminate free radicals, anti-aging, prolong life.
9. The effective prevention of female urogenital system bacterial infection.
10. Control the body endotoxin level, protect the liver and strengthening the liver detoxification, detoxification function. A few for special fermentation, such as intestinal membrane bright beads bacterium (Leuconostocmesenteroides) is the pharmaceutical industry production of dextran (that is, the generation of plasma) important species, but also is a kind of sugar industry against bacteria, often make the sugar juice hair sticky and will not be able to process. Rod of lactic acid bacteria, bacteria, singly or in chain, sometimes into filaments, produce false branches. According to the use of glucose after the product is different, divided into the same type of fermentation and fermentation of alien. Most kinds of lactose fermentation, and not using lactic acid, after fermentation pH can be dropped to below 6.0.