Micafungin is adumbrated for the analysis of candidemia, astute broadcast candidiasis, Candida peritonitis, abscesses and esophageal candidiasis.
Micafungin works by way of concentration-dependent inhibition of 1,3-beta-D-glucan synthase consistent in bargain accumulation of 1,3-beta-D-glucan, which is an capital polysaccharide absolute one-third of the majority of Candida spp. corpuscle walls.
This decreased glucan assembly leads to osmotic alternation and appropriately cellular lysis.Since January 23, 2008, micafungin has been accustomed for the prophylaxis of Candida infections in patients ability hematopoietic axis corpuscle transplantation (HSCT).
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