Wednesday, June 7, 2017

What is the role of Darunavir

What is the role of Darunavir? A lot of people don't know about this stuff, and here's the introduction to it:
Reed that wei chemical called [(1 r, 5 s, 6 r) - 2, 8 - two oxygen bicyclic [3.3.0 - decane - 6 - base - N - [(2 s, 3 r) - 4 - [(4 - amino phenyl) sulfonyl - (2 - methyl propyl) amino] - 3 - hydroxy - 1 - phenyl - butane - 2 - base] carbamate, CAS registration number is 206361-99-1, called Prezista goods.
Reed that is a kind of HIV - 1 protease inhibitors, selective inhibition of virus infected cells in HIV coding Gag - Pol much protein cracking, to prevent the formation of infectious virus particles of maturity. It binds to the hiv-1 protease, which has a Kp value of 4.5 x 10-12m. Reed that wei to protease inhibitors resistance mutations associated (RAM) has certain curative effect, but the wei of reed to the current detected 13 kinds of human cells protease no inhibition.

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