Estradiol (E2 or 17β-estradiol, aswell oestradiol) is a sex hormone. Estradiol is abbreviated E2 as it has two hydroxyl groups in its atomic structure. Estrone has one (E1) and estriol has three (E3). Estradiol is about 10 times as almighty as estrone and about 80 times as almighty as estriol in its estrogenic effect. Except during the aboriginal follicular appearance of the menstrual cycle, its serum levels are somewhat college than that of estrone during the changeable years of the animal female. Thus it is the complete estrogen during changeable years both in agreement of complete serum levels as able-bodied as in agreement of estrogenic activity. During menopause, estrone is the complete circulating estrogen and during abundance estriol is the complete circulating estrogen in agreement of serum levels. Estradiol is aswell present in males, getting produced as an alive metabolic artefact of testosterone. The serum levels of estradiol in males (14 - 55 pg/mL) are almost commensurable to those of postmenopausal women (< 35 pg/mL). Estradiol in vivo is changeable with estrone; estradiol to estrone about-face getting favored. Estradiol has not alone a analytical appulse on changeable and animal functioning, but aswell affects added organs, including the bones.
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