A brief introduction Alpha Arbutin

Alpha arbutin is similar to arbutin, can inhibit the generation of melanin and deposition, remove spots and freckles. Studies have shown that alpha arbutin in low concentrations can inhibit the activity of tyrosinase, of its inhibitory effect on tyrosinase is better than arbutin.

Ursolic acid in accordance with the structure can be divided into different type of alpha and beta, are enzymes enzyme inhibition of tyramine acid in order to achieve the whitening effect, applied the most were beta type, have detailed research; And allegedly alpha type is added to the beta type 1/9 concentration can inhibit tyramine acid enzymes, reach whitening effect, but haven't seen a detailed toxicology research.

Many add alpha ursolic acid maintain article all claims it has ten times higher than traditional ursolic acid whitening effect, and the efficacy but has not been clear data and experiment report confirmed, but the whitening effect is positive.

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From:Natural herbal extracts

A brief introduction Anti-DISC1（disrupted in schizophrenia1)

Disrupted in schizophrenia 1 is a protein that is encoded by the DISC1 gene in humans In coordination with a wide array of interacting partners, DISC1 has been shown to participate in the regulation of cell proliferation, differentiation, migration, neuronal axon and dendrite outgrowth, mitochondrial transport, fission and/or fusion, and cell-to-cell adhesion. Several studies have shown that unregulated expression or altered protein structure of DISC1 may predispose individuals to the development of schizophrenia, clinical depression, bipolar disorder, and other psychiatric conditions. The cellular functions that are disrupted by permutations in DISC1, which lead to the development of these disorders, have yet to be clearly defined and are the subject of current ongoing research.

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From:Elisa test kits

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From:Elisa test kits

A brief introduction Middlebrook 7h9 broth base

Middlebrook 7H9 Broth is a liquid growth medium specially used for culture of Mycobacterium, notably Mycobacterium tuberculosis.
7H9 broth supports the growth of mycobacterial species when supplemented with nutrients such as glycerol, oleic acid, albumin and dextrose, except for Mycobacterium bovis which is inhibited by glycerol. Cultures should be read within 5–7 days after inoculation and once a week thereafter for up to 8 weeks.
Middlebrook broth is commonly used in the preparation of inocula for antimicrobial assays, biochemical tests (arylsufatase and tellurite reduction) and for maintenance of stock strains.

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From:Natural herbal extracts

The purpose of Enalapril

Enalapril for angiotensin converting enzyme inhibitors (ACEI). In the body after oral hydrolysis into enalaprilat, have strong inhibition effect on angiotensin converting enzyme, reduce the content of angiotensin Ⅱ cause systemic vasodilation, blood pressure drops, used to treat high blood pressure.

To adapt to the symptoms: (1) used to treat high blood pressure, can be used alone or in combination with other antihypertensive agents such as diuretic and operable. (2) for the treatment of heart failure, and can be used alone or in combination with strong heart diuresis medicine share.

This product is suitable for various degree of hypertension, renovascular hypertension, and diabetes treatment for hypertension patients; Can also be used for the treatment of chronic congestive heart failure, especially in the conventional application of digitalis or diuretic is difficult to control, can delay the progress of clinical symptoms of congestive heart failure and minimize the need for hospitalization. Because this product effect is better than that of the captopril, adverse reactions and lighter, so it is increasingly widely used, in the treatment of high blood pressure drug of choice.

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From:pharmaceutical chemicals

Information about N,9-Diacetylguanine

CAS no. : 3056-33-5

English name: N, 9 - Diacetylguanine

English synonyms: 2, 9 - DAG. DIACETYL GUANINE. 9 - diacetylguanine; 2, 9 - DIACETYLGUANINE; N, 9 - DIACETYLGUANINE; N2, 9 - DIACETYLGUANINE; 2, 9 - DIACETATEGUANINE; 2, 9 - Guanine Diacetate; N (2) sup, 9 - diacetylguanine; 2 - Acetamido - 9 - acetyl - 6 - oxopurine

Chinese name: N, 9 - diacetyl guanine

English synonyms: 2, 9 - diacetyl guanine; N, 9 - diacetyl guanine; N2, 9 - diacetyl guanine; 2, 9 - two acetyl guanine; N - 2, 9 - two acetyl guanine; N (2), 9 - diacetyl guanine, 98%

CBNumber: CB6183086

Molecular formula: C9H9N5O3

Molecular weight: 235.2

MOL File: 3056-33-5. MOL

N, 9 - diacetyl guanine chemical properties

Melting point: 285 ° C (lit.)

Storage conditions: - 20 ° C Freezer

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From:Natural herbal extracts

Information about N,9-Diacetylguanine

CAS no. : 3056-33-5

English name: N, 9 - Diacetylguanine

English synonyms: 2, 9 - DAG. DIACETYL GUANINE. 9 - diacetylguanine; 2, 9 - DIACETYLGUANINE; N, 9 - DIACETYLGUANINE; N2, 9 - DIACETYLGUANINE; 2, 9 - DIACETATEGUANINE; 2, 9 - Guanine Diacetate; N (2) sup, 9 - diacetylguanine; 2 - Acetamido - 9 - acetyl - 6 - oxopurine

Chinese name: N, 9 - diacetyl guanine

English synonyms: 2, 9 - diacetyl guanine; N, 9 - diacetyl guanine; N2, 9 - diacetyl guanine; 2, 9 - two acetyl guanine; N - 2, 9 - two acetyl guanine; N (2), 9 - diacetyl guanine, 98%

CBNumber: CB6183086

Molecular formula: C9H9N5O3

Molecular weight: 235.2

MOL File: 3056-33-5. MOL

N, 9 - diacetyl guanine chemical properties

Melting point: 285 ° C (lit.)

Storage conditions: - 20 ° C Freezer

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From:Natural herbal extracts

Benzocaine is narcotics

Benzocaine is a bounded analgesic frequently acclimated as a contemporary affliction analgesic or in ahem drops. It is the alive additive in abounding over-the-counter analgesic ointments such as articles for articulate ulcers. It is aswell accumulated with antipyrine to anatomy A/B Otic Drops to abate ear affliction and abolish earwax.
Pain is acquired by the dispatch of chargeless assumption endings. When the assumption endings are stimulated, sodium enters the neuron, causing depolarization of the assumption and consecutive admission of an activity potential. The activity abeyant is broadcast down the assumption against the axial afraid system, which interprets this as pain. Benzocaine acts to arrest the voltage-dependent sodium channels (VDSCs) on the assumption membrane, endlessly the advancement of the activity potential.
Over-application of articulate anesthetics such as benzocaine can access the accident of pulmonary aspiration by adequate the gag-reflex and acceptance regurgitated abdomen capacity or articulate secretions to access the airway. Applying an articulate analgesic and arresting beverages afore traveling to bed can be decidedly hazardous. The articulate use of benzocaine articles has been begin to be a could cause of methemoglobinemia, a ataxia in which the bulk of oxygen agitated by the claret is abundantly reduced. This ancillary aftereffect is a lot of accepted in accouchement beneath 2 years of age.
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From:pharmaceutical chemicals

What is darifenacin?

Darifenacin is a medication acclimated to amusement urinary incontinence. It was apparent by scientists at the Pfizer analysis website in Sandwich, UK beneath the identifier UK-88,525 and ahead was marketed by Novartis; about in 2010 US rights for were awash to Warner Chilcott for 400 actor US$.

Mechanism of action:Darifenacin works by blocking the M3 muscarinic acetylcholine receptor, which is primarily amenable for float beef contractions. It thereby decreases the coercion to urinate. It is not accepted whether this selectivity for the M3 receptor translates into any analytic advantage if alleviative affection of overactive float syndrome.

It should not be acclimated in humans with urinary retention. Anticholinergic agents, such as Enablex, may aswell aftermath ache and blurred vision. Heat prostration (due to decreased sweating) can action if anticholinergics such as Enablex are acclimated in a hot environment.

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From:Natural herbal extracts

The use of norcantharidin instructions

Applicable disease: Norcantharidin on liver cancer, esophageal squamous carcinoma, cervical cancer, airy ascites carcinoma and sarcoma - 180 cell line shape or destroy or inhibit proliferation, reason for liver cancer, esophageal cancer, cardia cancer and stomach and low white blood disease, can also be used as preoperative medication or in combination chemotherapy. Preoperative medication can improve the survival rate. Share with other chemotherapy drugs can improve curative effect, reduce adverse reactions.

Note: 1. More than 45 mg, such as 1, some patients experience symptoms such as nausea, vomiting, withdrawal, reduction or symptomatic treatment, can disappear. 2. There are bone marrow suppression and urinary tract irritation. 3. The paroxysmal tachycardia, fingers and facial numbness, etc. 4. Heart renal insufficiency and pregnant women. Drink more green tea or water during the medication.

Usage and dosage: oral: 2 ~ 10 mg each time, 3 times a day. Static note or static drop: every time 5 ~ 20 mg, with a moderate amount of glucose solution diluted, 1 times a day.

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From:Natural herbal extracts

Information about Quinoline-3-carboxylic acid

The amalgam and in vitro antimicrobial appraisal of several quinoline and pyrimidoquinoline derivatives are described. Treatment of 7-substituted quinolin-2(1H)-one-3-carboxylic acids 2a-c with phosphoryl chloride or thionyl chloride gave acceleration to the Quinoline-3-carboxylic acid 3a-c and 7-substituted 2-chloro-3-chlorocarbonylquinolines 5a-c respectively. The 2-chloro action in compounds 3a-c was replaced by 2-aminothiazole or 2-aminopyridine to accord 2-(thiazol-2-yl)aminoquinoline-3-carboxylic acids 4a-c or 2-(pyrid-2-yl)aminoquinoline-3-carboxylic acids 4d-f. Treatment of 5a-c with the aforementioned heterocyclic amines at allowance temperature furnished the agnate 7-substituted 2-chloro-3-heteryl-aminocarbonylquinolines 6a-f. The tetracyclic 9-substituted thiazolo[3', 2':1, 2]-pyrimido[4, 5-b]quinolin-5-ones 7a-c and 10-substituted pyrido[1', 2':1, 2]-pyrimido[4, 5-b]quinolin-6-ones 7d-f were actinic by heating 5a-c with the heterocyclic amines in toluene or by heating 6a-f beneath abatement in dimethylformamide. The articles were evaluated in vitro for abeyant antimicrobial activity.

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From:Natural herbal extracts

Information about Tert-butyl hydroquinone( TBHQ)

TBHQ is prescribed by the state allows a small amount of adding edible antioxidants, compared with butylated hydroxytoluene, BHA, TBHQ have more safe non-toxic performance, because adding quantity is little. There used to be a famous domestic fast-food chain using German the sakura group of TBHQ was exposed by the media event. According to the American FDA regulations, TBHQ in oil or grease etc. The use of limit of 0.02% fat in food.  foreign studies have shown that with the increase of dose, TBHQ show the effect to the health of experimental animals, such as cancer of the stomach and the DNA damage.  compared with other antioxidants TBHQ shortcoming is narrow, it USES the industry are food, used in medicine and cosmetics industry with other antioxidants, such as butylated hydroxytoluene, tea polyphenols, but the price is quite high, tea polyphenols as antioxidant with butylated hydroxytoluene very widely.

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A brief introduction 1,2-Phenylenediamine dihydrochloride

Usage: used for organic synthesis, also used as a dye intermediates

Category: toxic substances

Toxicity grading: high toxic

Acute toxicity: abdominal - rats LD50:290 mg/kg. Abdominal cavity - LD50 in mice: 200 mg/kg

Flammability hazard characteristics: flame burning; Heat release toxic hydrochloric acid and nitrogen oxide gases

Storage and transportation characteristics: warehouse ventilated dry at low temperature; Separated from food raw material storage and transportation

Agent: fog water, carbon dioxide, sand and foam

CAS: 615-28-1

Name: OPD EASY-tablets

English Synonyms: OPD; OPD-HC1; OPD 2HCL; O-PD, HCL; OPD TABLET; usafek-678; OPD EASY-tablets; SIGMAFASTTM OPD; OPD DIHYDROCHLORIDE; OPD PEROXIDASE SUBSTRATE

Chinese name: o-phenylenediamine hydrochloride (reagent)

Chinese Synonyms: OPD tablets;-o-phenylenediamine hydrochloride;-o-phenylenediamine hydrochloride; hydrochloride o-diaminobenzene; o-phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride; 1, 2 - phenylethanol diamine hydrochloride; 1,2 - phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride (reagent)

CBNumber: CB9853980

Formula: C6H10Cl2N2

Molecular Weight: 181.06

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From:Chemical Reagent