Sunday, December 29, 2013

A brief introduction Alpha Arbutin




Alpha arbutin is similar to arbutin, can inhibit the generation of melanin and deposition, remove spots and freckles. Studies have shown that alpha arbutin in low concentrations can inhibit the activity of tyrosinase, of its inhibitory effect on tyrosinase is better than arbutin.
Ursolic acid in accordance with the structure can be divided into different type of alpha and beta, are enzymes enzyme inhibition of tyramine acid in order to achieve the whitening effect, applied the most were beta type, have detailed research; And allegedly alpha type is added to the beta type 1/9 concentration can inhibit tyramine acid enzymes, reach whitening effect, but haven't seen a detailed toxicology research.
Many add alpha ursolic acid maintain article all claims it has ten times higher than traditional ursolic acid whitening effect, and the efficacy but has not been clear data and experiment report confirmed, but the whitening effect is positive.

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From:Natural herbal extracts

Friday, December 27, 2013

A brief introduction Anti-DISC1(disrupted in schizophrenia1)



Disrupted in schizophrenia 1 is a protein that is encoded by the DISC1 gene in humans In coordination with a wide array of interacting partners, DISC1 has been shown to participate in the regulation of cell proliferation, differentiation, migration, neuronal axon and dendrite outgrowth, mitochondrial transport, fission and/or fusion, and cell-to-cell adhesion. Several studies have shown that unregulated expression or altered protein structure of DISC1 may predispose individuals to the development of schizophrenia, clinical depression, bipolar disorder, and other psychiatric conditions. The cellular functions that are disrupted by permutations in DISC1, which lead to the development of these disorders, have yet to be clearly defined and are the subject of current ongoing research.


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From:Elisa test kits

Thursday, December 26, 2013

A brief introduction Middlebrook 7h9 broth base




Middlebrook 7H9 Broth is a liquid growth medium specially used for culture of Mycobacterium, notably Mycobacterium tuberculosis.
7H9 broth supports the growth of mycobacterial species when supplemented with nutrients such as glycerol, oleic acid, albumin and dextrose, except for Mycobacterium bovis which is inhibited by glycerol. Cultures should be read within 5–7 days after inoculation and once a week thereafter for up to 8 weeks.
Middlebrook broth is commonly used in the preparation of inocula for antimicrobial assays, biochemical tests (arylsufatase and tellurite reduction) and for maintenance of stock strains.

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From:Natural herbal extracts

Monday, December 23, 2013

The purpose of Enalapril



Enalapril for angiotensin converting enzyme inhibitors (ACEI). In the body after oral hydrolysis into enalaprilat, have strong inhibition effect on angiotensin converting enzyme, reduce the content of angiotensin Ⅱ cause systemic vasodilation, blood pressure drops, used to treat high blood pressure.
To adapt to the symptoms: (1) used to treat high blood pressure, can be used alone or in combination with other antihypertensive agents such as diuretic and operable. (2) for the treatment of heart failure, and can be used alone or in combination with strong heart diuresis medicine share.
This product is suitable for various degree of hypertension, renovascular hypertension, and diabetes treatment for hypertension patients; Can also be used for the treatment of chronic congestive heart failure, especially in the conventional application of digitalis or diuretic is difficult to control, can delay the progress of clinical symptoms of congestive heart failure and minimize the need for hospitalization. Because this product effect is better than that of the captopril, adverse reactions and lighter, so it is increasingly widely used, in the treatment of high blood pressure drug of choice.

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Thursday, December 19, 2013

Information about N,9-Diacetylguanine



CAS no. : 3056-33-5
English name: N, 9 - Diacetylguanine
English synonyms: 2, 9 - DAG. DIACETYL GUANINE. 9 - diacetylguanine; 2, 9 - DIACETYLGUANINE; N, 9 - DIACETYLGUANINE; N2, 9 - DIACETYLGUANINE; 2, 9 - DIACETATEGUANINE; 2, 9 - Guanine Diacetate; N (2) sup, 9 - diacetylguanine; 2 - Acetamido - 9 - acetyl - 6 - oxopurine
Chinese name: N, 9 - diacetyl guanine
English synonyms: 2, 9 - diacetyl guanine; N, 9 - diacetyl guanine; N2, 9 - diacetyl guanine; 2, 9 - two acetyl guanine; N - 2, 9 - two acetyl guanine; N (2), 9 - diacetyl guanine, 98%
CBNumber: CB6183086
Molecular formula: C9H9N5O3
Molecular weight: 235.2
MOL File: 3056-33-5. MOL
N, 9 - diacetyl guanine chemical properties
Melting point: 285 ° C (lit.)
Storage conditions: - 20 ° C Freezer

Information about N,9-Diacetylguanine



CAS no. : 3056-33-5
English name: N, 9 - Diacetylguanine
English synonyms: 2, 9 - DAG. DIACETYL GUANINE. 9 - diacetylguanine; 2, 9 - DIACETYLGUANINE; N, 9 - DIACETYLGUANINE; N2, 9 - DIACETYLGUANINE; 2, 9 - DIACETATEGUANINE; 2, 9 - Guanine Diacetate; N (2) sup, 9 - diacetylguanine; 2 - Acetamido - 9 - acetyl - 6 - oxopurine
Chinese name: N, 9 - diacetyl guanine
English synonyms: 2, 9 - diacetyl guanine; N, 9 - diacetyl guanine; N2, 9 - diacetyl guanine; 2, 9 - two acetyl guanine; N - 2, 9 - two acetyl guanine; N (2), 9 - diacetyl guanine, 98%
CBNumber: CB6183086
Molecular formula: C9H9N5O3
Molecular weight: 235.2
MOL File: 3056-33-5. MOL
N, 9 - diacetyl guanine chemical properties
Melting point: 285 ° C (lit.)
Storage conditions: - 20 ° C Freezer

Tuesday, December 17, 2013

Benzocaine is narcotics


Benzocaine is a bounded analgesic frequently acclimated as a contemporary affliction analgesic or in ahem drops. It is the alive additive in abounding over-the-counter analgesic ointments such as articles for articulate ulcers. It is aswell accumulated with antipyrine to anatomy A/B Otic Drops to abate ear affliction and abolish earwax.
Pain is acquired by the dispatch of chargeless assumption endings. When the assumption endings are stimulated, sodium enters the neuron, causing depolarization of the assumption and consecutive admission of an activity potential. The activity abeyant is broadcast down the assumption against the axial afraid system, which interprets this as pain. Benzocaine acts to arrest the voltage-dependent sodium channels (VDSCs) on the assumption membrane, endlessly the advancement of the activity potential.
Over-application of articulate anesthetics such as benzocaine can access the accident of pulmonary aspiration by adequate the gag-reflex and acceptance regurgitated abdomen capacity or articulate secretions to access the airway. Applying an articulate analgesic and arresting beverages afore traveling to bed can be decidedly hazardous. The articulate use of benzocaine articles has been begin to be a could cause of methemoglobinemia, a ataxia in which the bulk of oxygen agitated by the claret is abundantly reduced. This ancillary aftereffect is a lot of accepted in accouchement beneath 2 years of age.
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From:pharmaceutical chemicals

Thursday, December 12, 2013

What is darifenacin?



Darifenacin is a medication acclimated to amusement urinary incontinence. It was apparent by scientists at the Pfizer analysis website in Sandwich, UK beneath the identifier UK-88,525 and ahead was marketed by Novartis; about in 2010 US rights for were awash to Warner Chilcott for 400 actor US$.
Mechanism of action:Darifenacin works by blocking the M3 muscarinic acetylcholine receptor, which is primarily amenable for float beef contractions. It thereby decreases the coercion to urinate. It is not accepted whether this selectivity for the M3 receptor translates into any analytic advantage if alleviative affection of overactive float syndrome.
It should not be acclimated in humans with urinary retention. Anticholinergic agents, such as Enablex, may aswell aftermath ache and blurred vision. Heat prostration (due to decreased sweating) can action if anticholinergics such as Enablex are acclimated in a hot environment.


The use of norcantharidin instructions



Applicable disease: Norcantharidin on liver cancer, esophageal squamous carcinoma, cervical cancer, airy ascites carcinoma and sarcoma - 180 cell line shape or destroy or inhibit proliferation, reason for liver cancer, esophageal cancer, cardia cancer and stomach and low white blood disease, can also be used as preoperative medication or in combination chemotherapy. Preoperative medication can improve the survival rate. Share with other chemotherapy drugs can improve curative effect, reduce adverse reactions.
Note: 1. More than 45 mg, such as 1, some patients experience symptoms such as nausea, vomiting, withdrawal, reduction or symptomatic treatment, can disappear. 2. There are bone marrow suppression and urinary tract irritation. 3. The paroxysmal tachycardia, fingers and facial numbness, etc. 4. Heart renal insufficiency and pregnant women. Drink more green tea or water during the medication.
Usage and dosage: oral: 2 ~ 10 mg each time, 3 times a day. Static note or static drop: every time 5 ~ 20 mg, with a moderate amount of glucose solution diluted, 1 times a day.

Monday, December 9, 2013

Information about Quinoline-3-carboxylic acid



The amalgam and in vitro antimicrobial appraisal of several quinoline and pyrimidoquinoline derivatives are described. Treatment of 7-substituted quinolin-2(1H)-one-3-carboxylic acids 2a-c with phosphoryl chloride or thionyl chloride gave acceleration to the Quinoline-3-carboxylic acid 3a-c and 7-substituted 2-chloro-3-chlorocarbonylquinolines 5a-c respectively. The 2-chloro action in compounds 3a-c was replaced by 2-aminothiazole or 2-aminopyridine to accord 2-(thiazol-2-yl)aminoquinoline-3-carboxylic acids 4a-c or 2-(pyrid-2-yl)aminoquinoline-3-carboxylic acids 4d-f. Treatment of 5a-c with the aforementioned heterocyclic amines at allowance temperature furnished the agnate 7-substituted 2-chloro-3-heteryl-aminocarbonylquinolines 6a-f. The tetracyclic 9-substituted thiazolo[3', 2':1, 2]-pyrimido[4, 5-b]quinolin-5-ones 7a-c and 10-substituted pyrido[1', 2':1, 2]-pyrimido[4, 5-b]quinolin-6-ones 7d-f were actinic by heating 5a-c with the heterocyclic amines in toluene or by heating 6a-f beneath abatement in dimethylformamide. The articles were evaluated in vitro for abeyant antimicrobial activity.

Thursday, December 5, 2013

Information about Tert-butyl hydroquinone( TBHQ)



TBHQ is prescribed by the state allows a small amount of adding edible antioxidants, compared with butylated hydroxytoluene, BHA, TBHQ have more safe non-toxic performance, because adding quantity is little. There used to be a famous domestic fast-food chain using German the sakura group of TBHQ was exposed by the media event. According to the American FDA regulations, TBHQ in oil or grease etc. The use of limit of 0.02% fat in food.  foreign studies have shown that with the increase of dose, TBHQ show the effect to the health of experimental animals, such as cancer of the stomach and the DNA damage.  compared with other antioxidants TBHQ shortcoming is narrow, it USES the industry are food, used in medicine and cosmetics industry with other antioxidants, such as butylated hydroxytoluene, tea polyphenols, but the price is quite high, tea polyphenols as antioxidant with butylated hydroxytoluene very widely.

More about:Tert-butyl hydroquinone( TBHQ) Suppliers From:Food Additives

Tuesday, December 3, 2013

A brief introduction 1,2-Phenylenediamine dihydrochloride



Usage: used for organic synthesis, also used as a dye intermediates
Category: toxic substances
Toxicity grading: high toxic
Acute toxicity: abdominal - rats LD50:290 mg/kg. Abdominal cavity - LD50 in mice: 200 mg/kg
Flammability hazard characteristics: flame burning; Heat release toxic hydrochloric acid and nitrogen oxide gases
Storage and transportation characteristics: warehouse ventilated dry at low temperature; Separated from food raw material storage and transportation
Agent: fog water, carbon dioxide, sand and foam
CAS: 615-28-1
Name: OPD EASY-tablets
English Synonyms: OPD; OPD-HC1; OPD 2HCL; O-PD, HCL; OPD TABLET; usafek-678; OPD EASY-tablets; SIGMAFASTTM OPD; OPD DIHYDROCHLORIDE; OPD PEROXIDASE SUBSTRATE
Chinese name: o-phenylenediamine hydrochloride (reagent)
Chinese Synonyms: OPD tablets;-o-phenylenediamine hydrochloride;-o-phenylenediamine hydrochloride; hydrochloride o-diaminobenzene; o-phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride; 1, 2 - phenylethanol diamine hydrochloride; 1,2 - phenylenediamine dihydrochloride; o-phenylenediamine dihydrochloride (reagent)
CBNumber: CB9853980
Formula: C6H10Cl2N2
Molecular Weight: 181.06



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From:Chemical Reagent

Thursday, November 21, 2013

The basic information of the Fmoc-Gln-OH





Chinese Name: FMOC-GLN-OH
English Synonyms :9-FLUORENYLMETHOXYCARBONYL-L-GLUTAMINE; FMOC-L-GLUTAMINE; FMOC-L-GLN; FMOC-L-GLN-OH; FMOC-GLUTAMINE; FMOC-GLN;
CAS No. :118609 -68-0 [1]
EINECS No. :276 -254-3
Molecular formula: C20H20N2O5
Molecular Weight: 368.3832
Density: 1.332g/cm3
Melting point: 220 ℃ (dec.) (lit.)
Boiling Point: 699.8 ° C at 760 mmHg
Flash Point: 377.1 ° C
Vapor Pressure: 1.47E-20mmHg at 25 ° C


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From:Biochemical Reagent

Wednesday, November 20, 2013

The basic information of the L-Glutamine methyl ester hydrochloride



CAS: 32668-14-7
Product Name: L-GLUTAMINE METHYL ESTER HYDROCHLORIDE
English Synonyms: H-GLN-OME HCL; L-GlutaMine Methyl ester; L-Glutamine Ethyl Ester HCl; L-GLUTAMINE METHYL ESTER HYDROCHLORIDE; L-Glutamine methyl ester monohydrochloride; L-Glutamine, methyl ester, hydrochloride (1:1) ; (S)-2-AMINO-4-CARBAMOYL-BUTYRIC ACID METHYL ESTER, HCL
Chinese Name: glutamic acid methyl ester hydrochloride
Chinese Synonyms: L-glutamic acid methyl ester hydrochloride; L-glutamine methyl ester hydrochloride; L-glutamine methyl ester monohydrochloride
CBNumber: CB1447978
Formula: C6H13ClN2O3


Sunday, November 17, 2013

The basic information of the Toll-Like Receptor 11 Polyclonal Antibody





English name: Toll-Like Receptor 11 Polyclonal Antibody,Toll-like receptor 11 (TLR 11) is a protein encoded by the gene TLR11. TLR 11 belongs to the Toll-like receptor (TLR) family and the Interleukin-1 receptor/Toll-like receptor superfamily. By recognizing flagellin and/or profilin present on certain microbes, it helps propagate a host immune response. TLR11 plays a fundamental role in both the innate and adaptive immune responses, through the activation of Tumor necrosis factor-alpha, the Interleukin 12 (IL-12) response, and Interferon-gamma (IFN-gamma) secretion. TLR11 mounts an immune response to multiple microbes, including Toxoplasma gondii (T. gondii), Salmonella species, and uropathogenic Escherichia coli (E. coli), and likely many other species due to the highly conserved nature of flagellin and profilin.


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From:Raw pharmaceutical materials

Thursday, November 7, 2013

Kinetin - Plant growth regulators is how to find out





Kinetin is a kind of natural cytokinins, chemical name is 6 - sugar amino purine base (or N6 - furan methyl adenine), molecular formula C10H9N5O. Insoluble in water, soluble in acid, alkali and glacial acetic acid; In addition to have to promote the role of cell division, but also has delay in vitro and the aging of cut blades, inducing bud differentiation and development, and increase the effect of stomatal opening.
Found the origin: in 1955, American scientists Skoog (f. s. Skoog) when doing tobacco pith tissue culture, found that the yeast extract can promote plant cell division, it turned out that play a role for DNA breakdown products, and analyze its components, namely, kinetin. It was the first to be discovered with cytokinin role of material. This material with high biological activities, belong to "the natural plant hormones.


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From:Natural herbal extracts

Tuesday, November 5, 2013

Estradiol can affect people's health




Estradiol (E2 or 17β-estradiol, aswell oestradiol) is a sex hormone. Estradiol is abbreviated E2 as it has two hydroxyl groups in its atomic structure. Estrone has one (E1) and estriol has three (E3). Estradiol is about 10 times as almighty as estrone and about 80 times as almighty as estriol in its estrogenic effect. Except during the aboriginal follicular appearance of the menstrual cycle, its serum levels are somewhat college than that of estrone during the changeable years of the animal female. Thus it is the complete estrogen during changeable years both in agreement of complete serum levels as able-bodied as in agreement of estrogenic activity. During menopause, estrone is the complete circulating estrogen and during abundance estriol is the complete circulating estrogen in agreement of serum levels. Estradiol is aswell present in males, getting produced as an alive metabolic artefact of testosterone. The serum levels of estradiol in males (14 - 55 pg/mL) are almost commensurable to those of postmenopausal women (< 35 pg/mL). Estradiol in vivo is changeable with estrone; estradiol to estrone about-face getting favored. Estradiol has not alone a analytical appulse on changeable and animal functioning, but aswell affects added organs, including the bones.

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From:Natural herbal extracts

Sunday, November 3, 2013

The summary of Platinum





Platinum is a actinic aspect with the actinic attribute Pt and an diminutive amount of 78.Its name is acquired from the Spanish appellation platina, which is actually translated into "little silver". It is a dense, malleable, ductile, precious, gray-white alteration metal.Platinum has six by itself occurring isotopes. It is one of the rarest elements in the Earth's band and has an boilerplate affluence of about 5 μg/kg. It is the atomic acknowledging metal. It occurs in some nickel and chestnut ores forth with some built-in deposits, mostly in South Africa, which accounts for 80% of the apple production.
As a affiliate of the platinum accumulation of elements, as able-bodied as of the accumulation 10 of the alternate table of elements, platinum is about non-reactive. It exhibits a arresting attrition to corrosion, even at top temperatures, and as such is advised a blue-blooded metal. As a result, platinum is generally begin chemically absolute as built-in platinum. Because it occurs by itself in the alluvial bank of assorted rivers, it was aboriginal acclimated by pre-Columbian South American citizenry to aftermath artifacts. It was referenced in European writings as aboriginal as 16th century, but it was not until Antonio de Ulloa appear a address on a new metal of Colombian agent in 1748 that it became advised by scientists.


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From:Chemical Reagent

Friday, November 1, 2013

The basic information of the Aminodiphenylmethane





CAS Number: 91-00-9
English name: Aminodiphenylmethane
English Synonyms: NSC 49127; AURORA KA-7667; BENZHYDRYLAMINE; Benzhydralamine; benzohydrylamine; TIMTEC-BB SBB006574; Benzhydrylamine, 97%; a-Phenylbenzylamine; diphenylMethylaMino; AMINODIPHENYLMETHANE
Chinese name: Aminodiphenylmethane
Chinese Synonyms: Aminodiphenylmethane; two methylamine; Benzhydrylamine; methyl diphenyl amine; aminodiphenylmethane; amino diphenyl methane; Α-phenyl benzylamine; Benzhydrylamine , 97%; Α-diaminodiphenylmethane; 1,1 - diphenyl amine
CBNumber: CB7409604
Formula: C13H13N
Molecular Weight: 183.25
MOL File: 91-00-9.mol
Aminodiphenylmethane chemical properties
Melting point: 12 ° C (lit.)
Boiling Point: 295 ° C (lit.)
Density: 1.063 g / mL at 25 ° C (lit.)
Refractive index: n20 / D 1.595 (lit.)
Flash point:> 230 ° F
Sensitivity: Air Sensitive


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From:pharmaceutical chemicals

Wednesday, October 30, 2013

Introduction of Ursolic acid





Ursolic acid -- --  loquat leaf extract; English name: Ursolic acid. Ursolic acid, also known as: ursolic acid WuSu acid, ursolic acid is a kind of triterpene compounds exist in the natural plant and it has the cancer resistance, resistance to promote cancer, induced F9 teratoma cell differentiation and anti-angiogenesis effect, is likely to be low toxicity and efficient new anti-cancer drugs. Pharmacological effects: triterpene compounds. Has a sedative, anti-inflammatory, antibacterial, anti diabetes, fight ulcer, reduce blood sugar and so on the many kinds of biological effects.
In addition, ursolic acid has obvious antioxidant functions, and therefore is widely used as a pharmaceutical and cosmetic ingredients. Direction: ursolic acid can significantly inhibit the HL 60 cell proliferation, can induce its apoptosis; Can make the macrophage phagocytosis of mice increased significantly. In vivo tests proved that ursolic acid can significantly boost the body's immune function.


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From:Natural herbal extracts

Friday, October 25, 2013

Atovaquone - d4 pharmacology is introduced




Atovaquone - d4 for hydroxyl 1, 4 - naphthalene, quinoline, is the homologue of the coenzyme Q is the activity of several kinds of parasite. On plasmodium, the role of parts for cytochrome BCL point (point Ⅲ). Atovaquone - d4 reversibility and can combine with peptides on 11500 da molecular group. Dihydrogen orotic acid dehydrogenase is important enzymes in the biosynthesis of pyridine, through coenzyme Q connecting mitochondrial electron transport, hence Atovaquone - d4 by inhibiting the electron transfer to prevent the synthesis of pyridine. Some metabolic enzymes through coenzyme Q in the mitochondrial electron transport, therefore, Atovaquone - d4 inhibitory effect of electron transfer is actually inhibits the activity of these enzymes.

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From:Natural herbal extracts

Wednesday, October 23, 2013

Hydromorphone related applications





Hydromorphone, a added accepted analogue for dihydromorphinone (not to be abashed by Dihydromorphine, which is a altered acquired of the morphine family), frequently a hydrochloride (brand names Palladone, Dilaudid, and abundant others) is a actual almighty centrally acting analgesic biologic of the opioid class. It is a acquired of morphine; to be specific, a hydrogenated ketone thereof, and it can be said that hydromorphone is to morphine as hydrocodone is to codeine and, therefore, a semi-synthetic drug. It is, in medical terms, an opioid analgesic and, in acknowledged terms, a narcotic. Hydromorphone is frequently acclimated in the hospital setting, mostly intravenously (IV) because its bioavailability orally, rectally, and intranasally is actual low. Sublingual administering is usually above to burning for bioavailability and effects.
Hydromorphone is abundant added acrid in baptize than morphine and accordingly hydromorphone solutions can be produced to bear the biologic in a abate aggregate of water.
Very baby quantities of hydromorphone are detected in assays of opium on attenuate occasions; it appears to be produced by the bulb beneath affairs and by processes which are not accepted at this time and may cover the activity of bacteria. A agnate action and/or added metabolic processes in the bulb may actual able-bodied be amenable for the actual low quantities of hydrocodone aswell begin on attenuate occasions in opium and alkaloid mixtures acquired therefrom; dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly added derivatives of morphine and/or hydromorphone aswell are begin in trace amounts in opium.


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From:Natural herbal extracts

Monday, October 21, 2013

The basic information of the Repertaxin



CAS no. : 266359-83-5
English name: Repertaxin
English synonyms: Reparixin; Repertaxin
Chinese name:
English synonyms:
CBNumber: CB82628350
Molecular formula:
Molecular weight: 0
MOL File: MOL File


Friday, October 18, 2013

Information of Lovastatin





Lovastatin is a new kind of adjusting blood fat drug listed in the eighty s, because of its unique curative effect, has been hailed as a milestone in the treatment of cardiovascular system diseases, was welcomed by the majority of patients.
This product competitively inhibit cholesterol synthesis in the body, the speed limit in the process of enzyme hydroxyl methyl glutaric acyl coenzyme A reductase, reduce cholesterol synthesis, also increase the low density lipoprotein receptor synthesis, the main working part in the liver, the result of blood cholesterol and LDL cholesterol levels, thus to atherosclerosis and coronary heart disease prevention and control work. This product also reduce blood serum triglyceride level and increase high density lipoprotein level. In mice, for 3-4 times people dose can cause cancer, but not in large-scale long-term clinical trials in humans, increased tumorigenesis. Mutation of the existing research did not find this product to have.


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From:Natural herbal extracts

Tuesday, October 15, 2013

Losartan drug ingredients





Losartan ( Cozaar ) ( English name : Losartan; Alias: Cozaar Losartan , Losartan ) Method : 1 - butyl-4 - chloro- 5 - (hydroxymethyl) imidazole and sodium methoxide in methanol the reaction solution was stirred , and then the resulting sodium salt and 4' - bromomethyl-2 - cyano- biphenyl in dimethyl formamide was stirred , the ether of the compound obtained , and then sodium azide and ammonium chloride -containing dimethyl formamide reaction, the acid hydrolysis of losartan . Purpose: Cozaar first listed in 1994 , is now in 93 countries have been approved for use for the treatment of hypertension . Oral non-peptide angiotensin Ⅱ receptor antagonist. Mainly used for essential hypertension . Cozaar is the first angiotensin Ⅱ receptor antagonist (AIIA) classes of antihypertensive drugs . Properties: light yellow solid , mp 183.5 ~ 184.5 ℃.
Pharmaceutical ingredients : endogenous renin - angiotensin system (RAS) activation of renin release by the kidneys . Renin from the liver can break down a protein called angiotensinogen , angiotensin decomposed product is I. Although angiotensin I itself has no biological activity, but it is a precursor of angiotensin II , and angiotensin II on vascular , cardiac and other body tissue with a series of biological activity. AIIA drugs such as Cozaar can block the angiotensin receptor (AT1), to avoid binding to receptors of angiotensin II , and ultimately achieve the purpose of preventing vasoconstriction .
Cozaar once a day , usually a dose of 50mg. Similar products Cozaar and Hyzaar is a small dose of diuretic ( hydrochlorothiazide ) combinations , also used to treat high blood pressure. Cozaar treatment alone can not properly control blood pressure in patients can try to use Hyzaar ( losartan 50mg / Hydrochlorothiazide 12.5mg) treatment.
Compared with other anti- hypertensive drugs , Cozaar and Hyzaar main advantage is its well tolerated , side effects is low.


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From:Natural herbal extracts

Monday, October 14, 2013

MatrixylAcetate (Palmitoyl Pentapeptide) The role of the skin




The role of peptide cream ingredients:
1, supple and smooth texture, quickly absorbed, forming skin lock water network;
2, the micro-molecular hydrolyzed collagen and palmitoyl pentapeptide binding, can promote the skin's own collagen production, the real bottom activate the skin from the muscle to the skin of energy;
3, there are a variety of moisturizing ingredients added anti Brightening essence, the real effective repair firm skin while improving skin's dull, long-lasting skin firming Xi stepped lip care.

Eye Hydra Decryption:
Micro-hydrolyzed collagen molecules with a variety of soothing moisturizing ingredients, eye skin instantly inject a large amount of collagen and moisturizing elements that promote eye skin metabolism, can significantly relieve eye fatigue, dry ..... palmitoyl pentapeptide, will enhance the hydrolysis the efficacy of collagen molecules, truly can promote the skin's own collagen formation, to delay the fine lines have a significant effect.



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From:Natural food additive

Wednesday, October 9, 2013

What is Fresh cheese?


Fresh cheese is a natural cheese category , also known as "fresh cheese ", " fresh cheese " is all other types of natural cheese foundation.
Fresh cheese is a fresh cheese has not been proven , it is sufficient water , sour refreshing taste fresh , low fat content . The most famous is the fresh cheese made ​​from cream cheese if the cream .
Fresh cheese popular in Europe . French-made white cheese (Fromage Frais) as white as its name , and there is a unique fragrance and taste of milk .
Italian production of mozzarella cheese (Mozzarella) was President of Spain, praised as " delicious masterpiece " and its fresh taste best suited as meals eaten directly. Mozzarella processing very elegant, used for pizza is also very good .
The world -renowned French-made fresh cheese with white cheese (Fromage Frais), (St Moret), Bulu Xi Cheese (Boursin), made ​​in Italy Rui Keta Cheese (Ricotta), Muscat Capone cheese (Mascarpone), mozzarella cheese (Mozzarella), Denmark produced DOFO cream cheese (DOFO Cream), feta cheese (Denmark Feta), global production of cottage cheese (Cottage Cheese) and so on.



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From:Food bacteria

Tuesday, October 8, 2013

The clinical significance of Estradiol




Estradiol transdermal estrogen therapy agent. Supplementary female ovarian secretion of 17-β estradiol deficiency , while avoiding the side effects caused due to oral ( breast pain , weight gain , high blood pressure , gallstones and liver dysfunction , etc. ) . Estrogen can induce cells to synthesize DNA, RNA and associated proteins found in the various tissues .

Clinical significance :
1 . Increase seen in female precocious puberty, gynecomastia , pregnancy ( especially in twins or multiple births ) , tumor secretion of estrogen , ovulation drugs ( such as chlorine Griffin ) , the feminization of men , ovarian tumors, anovulatory dysfunctional uterine bleeding and liver cirrhosis and so on.
2 . Reduction seen in ovarian cancer, mole, intrauterine fetal death , pregnancy-induced hypertension syndrome , hypothalamic tumors, pituitary function of reduced ovarian dysfunction , oophorectomy , delayed puberty , primary and secondary amenorrhea , menopause , oral contraceptive medicine. [ 2 ]
3 , estradiol values ​​increased pathological cause a ) ovarian disorders : ovarian granulosa cell tumor , ovarian germ tumors , ovarian fat-like cell tumors , tumors and other sex hormones , ovarian function showed hyperactivity , increased secretion of estradiol . 2 ) Heart disease: myocardial infarction, angina , coronary artery stenosis. 3 ) Other: systemic lupus erythematosus , cirrhosis, male obesity.
4 , estradiol reduces pathological cause a ) ovarian disease : ovarian agenesis or hypoplasia , primary ovarian failure , ovarian cysts. 2 ) pituitary amenorrhea or infertility. 3 ) Other: A low- or hyperthyroidism, Cushing's syndrome, Addison's disease , cancer, a wide range of infections, renal dysfunction , brain and pituitary of focal lesions , etc., can make plasma estradiol reduce alcohol


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From:Herbal extract

Thursday, August 29, 2013

Pharmacological effects Terlipressin Acetate



Into the portal circulation in patients with cirrhosis of the vein and venous congestion may occur between the vascular anastomosis, portal venous pressure phenomenon. Occurs most frequently in the azygos vein anastomosis with esophageal between the esophageal varices. They become thick after expansion may rupture into the esophagus, causing vomiting life-threatening. Injection of pituitary hormone vasopressin can control bleeding. It causes severe contraction of visceral blood vessels thereby reducing portal pressure. However, after injection of vasopressin very short duration of action, and can cause side effects, such as angina, coronary artery contraction and increased fibrinolytic. This product is a prodrug of vasopressin, injected into the blood in the molecule glycyl generated by the enzyme-catalyzed hydrolysis sustained low levels of vasopressin. It portal venous pressure to produce the desired effect, but changes in arterial blood pressure is much smaller than the use of vasopressin and blood fibrinolytic few not increase. Bolus once its role can be maintained approximately 4 ~ 6h.

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Tuesday, August 27, 2013

Carboplatin traits and applications




Appearance: white or almost white powder or crystalline powder, odorless, tasteless, soluble in water, insoluble in ethanol, acetone, ether, chloroform; easy to decompose when exposed to light.
Carboplatin is a second-generation platinum compound, in 1986 in the UK, and its biochemical and physical characteristics similar to cisplatin, but nephrotoxicity, ototoxicity, neurotoxicity, especially gastrointestinal reactions was significantly lower than the DDP, widespread attention in recent years, new drugs, and DDP belong to the cell cycle non-specific drugs. It is the main role of DNA guanine N7 and O6 atoms, causing DNA chains and chain crosslinking damage DNA molecule helix melting prevent its interfering with DNA synthesis, and cytotoxicity.
Carboplatin as a broad-spectrum anti-tumor, with no cross-resistance to other antineoplastic agents, with DDP cross-resistance, easy to dissolve the drug, without hydration, hydration Lee, diuretic, easy to use.
(1) is mainly used for small cell lung cancer, ovarian cancer, testicular cancer, head and neck squamous cell carcinoma and so on. Small cell lung cancer, the FDA response rate was 60% single; with Vp-16, IFO combination therapy overall response rate was 78%; epithelial ovarian cancer, head and neck squamous cell carcinoma alone produced remission rates were 65%, 29%.
(2) can be used for non-small cell lung cancer, bladder cancer, cervical cancer, pleural mesothelioma, melanoma and endometrial cancer.
(3) can also be used for digestive system cancer, liver cancer therapy and radiation efficiency.


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Sunday, August 25, 2013

EPLERENONE pharmacological effects

Pharmacological effects:
EPL(EPLERENONE) is a selective aldosterone receptor antagonist, it only applies to the mineralocorticoid receptor, and not acting on the androgen and progesterone receptors. EPL treatment 1 and 2 hypertensive patients, efficient and lower systolic and diastolic blood pressure with enalapril similar magnitude. Angiotensin converting enzyme inhibitors and angiotensin Ⅱ receptor inhibitor effect of poor low renin levels in patients with essential hypertension, EPL also has a good antihypertensive effect. For isolated systolic hypertension has a good antihypertensive effect of diet-induced obesity-related hypertension have a good antihypertensive effect. In addition, EPL can significantly reduce glomerular ultrafiltration, reduce albuminuria in patients with hypertension, for hypertensive patients with diabetes, renal protective effect of this is more obvious.
Indications:
    1, acute myocardial infarction, congestive heart failure after: eplerenone can improve left ventricular dysfunction (ejection fraction ≤ 40%) the quality of life of patients, clinical trials demonstrate that the product can also be used for heart failure after acute myocardial infarction after acute myocardial infarction, congestive heart failure;
    2, anti-hypertension: Eplerenone may be used alone or with other antihypertensive drugs in combination for the treatment of hypertension.


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Thursday, August 22, 2013

Troxerutin purposes and pharmacological




Troxerutin for cerebral thrombosis and cerebral embolism caused by hemiplegia, aphasia, and myocardial infarction premenstrual syndrome, arteriosclerosis, central retinitis, thrombophlebitis, varicose veins, increased vascular permeability caused by edema.
For cerebral thrombosis caused by hemiplegia, aphasia, atherosclerosis, pre-infarction syndrome, thrombophlebitis, varicose veins, chronic venous insufficiency, central retinitis, diabetic retinitis and increased vascular permeability caused by the edema. This product is by clinical application showed wide range of applications, good effect, especially for the treatment of occlusive cerebrovascular disease better.
Pharmacology Pharmacokinetics: inhibition of platelet aggregation, to prevent thrombosis while to confront 5 - hydroxytryptamine, bradykinin induced vascular injury, increased capillary resistance, reducing capillary permeability, prevents vascular permeability resistance caused by elevated edema in acute ischemic brain injury has a significant protective effect.

ACTION: The strains of rutin hydroxyethylation made ​​by semi-synthetic flavonoids, red blood cells and platelet aggregation inhibiting role in preventing thrombosis, and can increase the oxygen content in the blood, improve microcirculation, promote angiogenesis to enhance the collateral circulation. It has a protective effect of endothelial cells that can fight 5 - serotonin and bradykinin induced vascular injury, increased capillary resistance, reducing capillary permeability, increased vascular permeability has prevented edema caused effect, and have anti-radiation damage, anti-inflammatory, anti-allergic, anti-ulcer and other effects.



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Tuesday, August 20, 2013

Some indications ARTEMETHER





ARTEMETHER is an efficient, quick erythrocytic stages of Plasmodium biocides. For chloroquine resistant Plasmodium falciparum and dangerous type of malaria treatment, effective in quickly, the recent good effect.
Indications: ARTEMETHER applicable to all types of malaria, but mainly for the treatment of falciparum malaria resistance to chloroquine and dangerous type of falciparum malaria treatment.
ARTEMETHER against falciparum malaria (including Plasmodium falciparum resistance to chloroquine and dangerous type of malaria) in better efficacy, the exact effect, effective rapid short-term efficacy of up to 100%. After two days of treatment in the majority of cases the blood parasite clearance and fever. Recrudescence rate of 8%. Lower than artemisinin. With primaquine recrudescence rate can be further reduced.
Also clinical trial in patients with acute upper respiratory tract infection fever patients, symptomatic treatment, achieve better results. Antipyretic effect usually in about half an hour after intramuscular injection that is beginning to emerge, trapezoid body temperature gradually decreased, from 4 to 6 hours or so and then gradually picked up, no sudden drop in body temperature phenomenon, cooling effect and stability. This product is sweat less in patients after intramuscular injection, without causing the elderly, children, frail patients experienced adverse reactions such as exhaustion.
With artemisinin. Can still be used to treat schistosomiasis.


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From:Natural herbal extracts

Tuesday, August 13, 2013

Whar is Ceftobiprole Medocaril?




The ameliorative action of ceftobiprole medocaril, the water-soluble prodrug of ceftobiprole, was compared to that of vancomycin in a rat tissue cage archetypal of abiding methicillin-resistant Staphylococcus aureus (MRSA) foreign-body infection. The MICs and MBCs of ceftobiprole and vancomycin in Mueller-Hinton borsch for ache MRGR3 were 1 and 4 and 1 and 2 microg/ml, respectively. In vitro abolishment ante of ache MRGR3 of 4 and 8 microg/ml of ceftobiprole or vancomycin were equivalent. After 2 weeks of infection, beggarly +/- accepted absurdity of the beggarly applicable counts of ache MRGR3 were 6.83 +/- 0.11 log CFU/ml of tissue cage aqueous (n = 87). High-dose regimens of ceftobiprole medocaril (equivalent to 150 mg/kg of ceftobiprole) or 50 mg/kg vancomycin produced about identical boilerplate aiguille and canal levels of ceftobiprole and vancomycin in tissue cage fluid, which exceeded the MBC of either antibacterial appear ache MRGR3 for > or =75% of anniversary dosing interval. After 7 canicule of analysis with ceftobiprole medocaril or vancomycin, boilerplate counts of MRGR3 decreased decidedly (P < 0.02) by 0.68 +/- 0.28 (n = 29) and 0.88 +/- 0.22 (n = 28) log CFU/ml of tissue cage fluid, respectively, compared with cages of basic animals, but were not decidedly altered from anniversary other. No aggressive mutants were detected on ceftobiprole-supplemented agar afterward analysis with this cephalosporin. The in vivo action of ceftobiprole medocaril adjoin abiding MRSA foreign-body infections was agnate to that of vancomycin and did not advance to the actualization of aggressive subpopulations.

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Monday, August 12, 2013

Dydrogesterone efficacy indications and usage, etc.


Dydrogesterone is an oral progesterone, can endometrium into secretory phase completely, thus preventing the estrogen-induced endometrial hyperplasia and cancer risk. Dydrogesterone for endogenous progesterone deficiency of various diseases. Dydrogesterone without estrogen, androgen and glucocorticoid effect. Dydrogesterone no heat, and no effect on lipid metabolism.
Effect Indications: dydrogesterone for the treatment of endogenous progesterone deficiency caused by diseases such as dysmenorrhea, endometriosis, secondary amenorrhea, irregular menstrual cycles, dysfunctional uterine bleeding, premenstrual syndrome progesterone deficiency threatened abortion or habitual abortion, infertility due to lack of corpus luteum.
Dosage: dysmenorrhea, menstrual cycle from the first 5-25 days, 2 times a day, each oral dydrogesterone 1 (count to dydrogesterone 10 mg). Endometriosis from the first 5-25 days of the menstrual cycle, daily oral dydrogesterone 2-3 times per oral dydrogesterone 1 (count to dydrogesterone 10 mg). Functional bleeding hemostasis dose: Each oral dydrogesterone 1 (count to dydrogesterone 10 mg), 2 times a day, 5-7 consecutive days. The dose to prevent bleeding: From the first 11-25 days of the menstrual cycle, each oral dydrogesterone 1 (count to dydrogesterone 10 mg), twice daily. Amenorrhea, menstrual cycle from 1-25 days, daily doses of estradiol, day 1. From the first 11-25 days of the menstrual cycle, the joint land dydrogesterone, 2 times a day, each one (with dydrogesterone total 10 mg). Premenstrual syndrome, menstrual irregularities from the first 11-25 days of the menstrual cycle, daily oral dydrogesterone two times, each one (with dydrogesterone total 10 mg). Threatened abortion as a starting dose oral 4 felled dydrogesterone (count to dydrogesterone 40 mg), then every 8 hours for 1 felled dydrogesterone (count to dydrogesterone 10 mg), until the symptoms disappears. Habitual abortion daily oral megestrol 2 times a (to dydrogesterone meter 10 mg), to 20 weeks of pregnancy. Endogenous progesterone deficiency causes infertility menstrual cycle 14-25 days, daily oral dydrogesterone 1 (to dydrogesterone meter 10 mg). Treatment should continue for at least six consecutive cycles, it is recommended in the first few months of pregnancy in a row using this method of treatment, the dose should refer to habitual abortion therapeutic dose.



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Tuesday, August 6, 2013

Voriconazole n-Oxide basic information




CAS Number: 618109-05-0
Name: Voriconazole N-Oxide
English synonyms: UK 12126; UK 121265; Voriconazole N-Oxide; (aR, S)-a-(2,4-Difluorophenyl)-5-fluoro - methyl-a-(1H-1 ,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol; (αR, βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-Methyl-α-(1H-1 ,2,4-triazol-1-ylMethyl)-1-oxide-4-pyriMidineethanol; (aR, bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1 ,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol
Chinese name:
Chinese Synonyms:
CBNumber: CB41176858
MF: C16H14F3N5O2
MW: 365.314
MOL File: 618109-05-0.mol
Voriconazole N-Oxide Chemical Properties
Melting Point: 75-77 ° C
Storage conditions: -20 ° C Freezer, Under Inert Atmosphere


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Monday, August 5, 2013

The clinical application of winstrol



winstrol is white or almost white crystalline powder, odorless. Almost insoluble in water, soluble in alcohol, chloroform, slightly soluble in acetone. Confined stored. This product anabolic activity of the male role of strong and weak differentiation index of about 120. For the treatment of a variety of related vascular diseases, such as Behcet's syndrome (Behcet syn-drome) in the vascular phenomena, hereditary angioneurotic edema, Raynaud's syndrome, superficial thrombophlebitis, venous ulcers . Can be used for chronic wasting disease, osteoporosis, and treatment with growth hormone Turner syndrome common (Turn-erssyndrome)
Clinical Applications: female patient application androgenic or anabolic hormones, can cause masculine phenomenon, such as hirsutism, a long beard, sound thicker and low tone, acne, usually in withdrawal symptoms may gradually subside. Male patients with long-term use of this class of hormones, drugs may be converted to estrogen in the body, and may inhibit gonadotropin secretion caused testicular atrophy and inhibition of spermatogenesis; due to suppression of endogenous testosterone production, can lead to impotence; Children's long-term application androgens, can seriously affect growth and development, such as acceleration acting on epiphyseal closure can still persist for several months after stopping; application anabolic hormones, can lead to obesity. 17 There are α-methyl androgen effects on the liver damage is more serious interference with intrahepatic bile capillary major excretory function, so that the central lobular capillary cholestasis in bile duct, resulting in cholestatic liver cell damage, clinical manifestations of bile cholestatic hepatitis. Long-term use of androgen, may be liver cancer, prostate cancer and renal cell carcinoma. In addition, because there is sodium retention effect, can cause edema. Used with caution in patients with kidney disease and heart failure, prostate cancer, pregnant women were banned.



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Thursday, August 1, 2013

Naphyrone in the UK



Naphyrone aswell accepted as O-2482 and naphthylpyrovaleroneis a biologic acquired from pyrovalerone that acts as a amateur reuptake inhibitor, bearing analeptic furnishings and has been appear as a atypical artist drug. No assurance or toxicity abstracts is accessible on the drug.

The biologic has been marketed beneath the name NRG-1, although alone a boyhood of samples of substances awash beneath this name accept been begin to in fact accommodate naphyrone, and even samples that accepted to accommodate 18-carat β-naphyrone were in some cases aswell begin to accommodate the 1-naphthyl isomer α-naphyrone in capricious proportions, added ambagious the appear furnishings profile.

Use in the United Kingdom:
Naphyrone emerged as a new acknowledged top in the United Kingdom alone months afterwards the ban of agnate biologic mephedrone (which was aswell a cathinone derivative). Until July 2010 the actuality was not controlled by the Misuse of Drugs Act 1971 and was accordingly not actionable for anyone to possess. The Medicines Act prevented naphyrone from getting awash for animal consumption, and accordingly it was sometimes awash as 'pond cleaner' or as addition actuality not commonly captivated by humans. In acknowledgment to this arising trend of new acknowledged highs, Home Office Minister James Brokenshire said "Action to abode the affair of arising acknowledged highs advancing on to the bazaar is a antecedence for the Government."

A accumulation assay address from the drugs advice website Drugs-Forum.com anachronous 12 June 2010 begin that some articles labelled as NRG-1 accommodate the Class B substances MDPV and flephedrone.In the case of an alone possessing a artefact labelled NRG-1 that contains MDPV, they are in control of a controlled substance. A consecutive abstraction by advisers at Liverpool John Moores University begin that alone one out of ten articles labelled as "NRG-1" in fact independent naphyrone if they were subjected to class analysis. Compounds begin in articles labelled NRG-1 included MDPV, flephedrone, mephedrone, butylone and caffeine, one artefact activated was asleep in composition.



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Tuesday, July 30, 2013

Policresulen on the application in gynecology




Gynecological medicine: Policresulen is a new drug treatment of cervical erosion, non-toxic, does not cause allergies and drug resistance of diseased tissue necrosis or selective, enabling condensation off the diseased tissue, but also causing local congestion, stimulate granulation tissue proliferation, accelerate skin coverage, but does not damage normal tissue. This product is also through high acid and protein coagulation and kill bacteria, mold and trichomoniasis, and has astringent, hemostatic effect. For the treatment of cervical erosion, vaginal variety of inflammatory or bleeding after biopsy. Can also be used to treat small burns, limb ulcers, bedsores and chronic dermatitis.
Uses various hospital departments a list of situations:
Gynecological medicine: for the treatment of cervical erosion, cervicitis, various vaginal infections (such as bacteria, mold and mildew caused by Trichomonas increased vaginal discharge), genital itching, caused by the use of a pessary pressure ulcers and cervical polyps after resection or biopsy hemostasis.
Surgery and Dermatology: Skin wounds and lesions for local treatment (such as burns, limb ulcers, bed sores, chronic inflammation), can accelerate the shedding of necrotic tissue, bleeding and facilitate the healing process.
ENT: used to treat inflammation of the oral mucosa and gums, mouth ulcers and bleeding after tonsillectomy.
Adverse reactions: medication early local irritation were seen, but soon go away. When policresulen for oral lesions, should pay attention to their high acidity can damage tooth enamel.


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From:Natural herbal extracts

Sunday, July 28, 2013

Salinomycin saodium prospects



Salinomycin saodium of monocarboxylic polyether animal-specific antibiotics, the majority of Gram-positive bacteria and a variety of coccidia have strong inhibitory and killing effect, easy to produce drug resistance and cross-resistance, rapid excretion, residual very low for pigs can prevent diarrhea, promote growth, improve the survival rate, mainly for poultry against coccidiosis U.S. researchers found a way to "targeting" and kill cancer stem cells compounds in the laboratory during the study period, the kill mice effectiveness of breast cancer stem cells than normal anti-cancer drug Taxol (Taxol) 100 times higher. Salinomycin saodium the body can not only kill cancer cells in mice, they also inhibit tumor cell gives rise to new, existing while slowing tumor growth.

Application Prospects:
With the accelerated pace of economic globalization, China has also been a rapid development of animal husbandry. Accelerate the export of livestock and poultry products, the promotion of Chinese rural problems, and promote comprehensive development of China's economy has major significance. However, more and more antibiotics are widely used in the treatment and prevention of various diseases of livestock, drug residues in animal products that affect international trade an important factor. Some Western industrial countries on antibiotics in animal products increasingly strict requirements, food of animal origin detection of antibiotic residues, has become the world meat trade in important technical indicators and one technical barriers.
China lags behind the development, large-scale livestock farming is not high, feeding and management level is low, the dosage is not standardized, the withdrawal of other problems, drug residues difficult to achieve the requirements of developed countries, leading to difficult access to developed country exports of livestock and poultry products of the market, even some veteran has entered the international market leading products are also forced to withdraw. This issue has become a constraint on China's export of animal products bottleneck.
Therefore, in the aquaculture industry select low toxicity and residue, broad-spectrum antibiotics, is the key to solve this bottleneck. While domestic quality medicines is still less than the current total feed salinomycin gap of 11,000 tons; China is a major exporter of antibiotics, one in Europe and enjoys a high reputation in the market, there are also considerable international market demand; salinomycin production process is relatively Simple, easy to master technology, the use of agricultural products and raw materials are all ordinary simple inorganic raw materials, non-toxic and harmless; Therefore, salinomycin breed development is conducive to people's livelihood, is the veterinary profession of veterinary drugs currently irreplaceable species.



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Friday, July 26, 2013

Some of the human placenta extracts.




Human placental medical scientists found, human placenta andcarnivorous almost. The difference is, contains a variety of vitamins and enzymes in human placenta, such as follicle stimulating hormone, luteinizing hormone, prolactin, lysozyme,kininase, protease. Main functions: 1, anti infection effect of placental gamma globulin containing measles, influenza antibodyand diphtheria antitoxin, can be used to prevent or reducemeasles and other infectious diseases. Because of the protein, sooral invalid, must injection. Placental gamma globulin also contains interferon, clinical on can be used for the prevention orcontrol of viral infection. The placenta also contain lysozyme, can prevent mice (i.p.) caused by enteritis of death
Enhance the body resistance to mice orally: placenta powder, can reduce tuberculosis lesions, and in vitro can promote the growthof Mycobacterium tuberculosis, so that its main function is toincrease the body resistance. Hydrochloric acid hydrolysis product of placenta after degreasing, rats were given intraperitoneal injection of carbon tetrachloride and B, caused by sulfur amino acid based liver fat deposition, has the obvious inhibitory action.Mice were given a subcutaneous injection of human placenta extracts, can prolong the swimming time of rats; intramuscular injection, on some experiments (reserpine, tonic, pylorus ligationlower) experimental ulcer, also have the effect of preventing and treating certain
In vitro, placenta extract can promote recovery of inhibited the heart. Placental protein, containing a pressor substance reninkind, in the regulation of blood circulation, and its significanceremains to be further elucidated. Human placenta is aglycoprotein containing ingredients, in vitro, inhibition oflymphocyte DNA synthesis, but does not affect cell viability.Heating the placenta extract can inhibit the methamphetaminecaused a great deal of time. Refrigerated placental pepsin digestion liquid, water extract and 70% acetone extract withWarburg apparatus sensing, respiratory and yeast could promote the liver, heart, brain and several kinds of tissue respiration is not frozen, refrigerated effect strong. Placenta Serum excitatory effect on the isolated guinea-pig uterus, similar posterior pituitary hormone. Chorionic villi of placenta extract is significant for cancer patients compared to healthy skin reaction, has certain diagnosticvalue, can continue to study, improve its specificity.



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