Propylparaben is white clear or powder, slight appropriate smell. Acrid in ethanol, propylene glycol and sodium hydroxide, hardly acrid in water. Mainly acclimated for antiseptic, augment preservative, antibacterial aftereffect is greater than Ethylparaben.
Propylparaben aswell accepted paraben, due to its accepting a phenolic hydroxyl structure, so the anti-bacterial backdrop than benzoic acid, sorbic acid, are stronger. Its apparatus of action: the abolition of the microbial corpuscle membranes, intracellular protein denaturation, and can arrest the respiratory enzymes of the electron carriage action of enzymes in microbial cells. Nipagin ester antibacterial action is primarily a atomic function, and a hydroxyl accumulation aural the atom accept been esterified, best ionization in the ambit of pH3 ~ 8, so it has actual acceptable antibacterial effect. Benzoic acerbic and sorbic acerbic are acerbic preservatives, pH> 5.5 poor inhibitory effect. The top aegis of the paraben ester, ethyl ester, for example, the LD50 5000mg / kg ADI of 0 to 10 mg / kg, benzoic acerbic LD50 of 2530mg / kg ADI of 0 to 5 mg / kg, Yamanashi the LD50 of the acerbic to 7630mg / kg, ADI 0 ~ 25mg / kg, Nipagin ester added bulk of alone sorbic acid, benzoic acid, 1/10 to 1/5, so its about assurance than sorbic abundant college .
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From: Cosmetics additives
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