Saturday, February 18, 2012

What is Polyvinylpyrrolidone?

Polyvinylpyrrolidone (PVP), also commonly called Polyvidone or Povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
Properties
PVP is soluble in water and other polar solvents. When dry it is a light flaky powder, which readily absorbs up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. PVP is a branched polymer, that is its structure is more complicated than linear polymer but it too is in a two-dimensional plane. The structure of a polymer greatly depends on its integrity and strength, formed through cross-links and bonds.
Polyvinylpyrrolidone is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally.
It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.
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