Escalol 507 is an ester organic compound related to the water soluble compound PABA (4-aminobenzoic acid), and used as an ingredient in some sunscreens. It is also called 2-ethylhexyl dimethyl PABA;Padimate O and Sundown. This yellowish water-insoluble oily liquid is formed by the condensation of 2-ethylhexanol and dimethylaminobenzoic acid. It is a yellowish oily liquid that is insoluble in water. It absorbs ultraviolet rays, thereby preventing direct DNA damage by UV-B. Unfortunately the excited Escalol 507 molecule reacts bimolecularly with DNA and produces indirect DNA damages, that are similar to those done by ionizing radiation. Therefore padimate O is presumably photocarcinogenic.This compound does not dissipate energy as fast as melanin, and therefore it is unsuitable as a sunscreen ingredient.
CAS: 21245-02-3; MF: C17H27NO2; MW: 277.4; EINECS: 244-289-3; Density: 0.99 g/cm?. approved use level: up to 8.0%. Use level in combination with other sunscreen actives: 1.4- 8.0%. Approval Status: Globally approved.
Escalol 507 is a powerful oil-soluble UV-B absorber. Provides cost-effective performance. Excellent safety profile. Category I sunscreen in the US; use at 1.4-8%. Approved worldwide. This product is at good quality and the price is reasonable.
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