Emtricitabine is by American Gilead Siences company successfully developed a new type of nuclear nucleoside reverse transcriptase inhibitors, antiviral drugs, on HIV, HIV - 1-2 and has antiviral activity, HBV antiviral activity in its specificity to HIV - 1, 2 and HBV, HIV - and its drug concentration to mnol 100 / L, also did not see it on HSV - 1, 2, HCMV, VZV HSV -, corona, yellow fever virus, respiratory syncytial virus, Rota, or nasal influenza virus virus activity. Even lower than the molar concentration, the drug also showed the LAV and Ⅲ B strains of HIV 1 and HIV - 2 ROD2 and potent inhibition of ZY strains, the IC50 alue concentration is lower than AZT (zidovudine) 95 times.
Emtricitabine associated with other antiretroviral drugs for the treatment of adults infected with HIV - 1.
Emtricitabine does not affect liver microsomal enzyme P450 enzyme system, do not produce the mediated drug interactions, and tenofovir fluorine wei, indene to the temple, pan yesterday, respectively.there company, share, pharmacokinetic almost had no effect.
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