Sunday, April 9, 2017

What is the Felodipine

The chlorine horizon; 4 - (2, 3 - two chlorobenzene) - 1, 4 - dihydro - 2, 6 - dimethyl - 3, 5 - pyridine carboxylic ethyl methyl ester; 4 - (2, 3 - two chlorobenzene) - 1, 4 - dihydro - 2, 6 - dimethyl - 3, 5 - pyridine dicarboxylic acid ethyl methyl ester
Felodipine for selective calcium ion antagonist medicine, principal restrain small artery smooth muscle cells of calcium in flow, selective expansion of small artery, the vein had no effect, not cause orthostatic hypotension; Also no obvious inhibitory effect on myocardial. This product in the lower renal vascular resistance at the same time, will not affect the glomerular filtration rate and creatinine clearance rate, there were no changes in renal blood flow increases slightly, even have a effect on promoting urinary sodium excretion and diuresis. This product can increase the output and cardiac index, significantly reduced after the load, and the cardiac systolic function, preload and heart rate had no obvious effect.

No comments:

Post a Comment