Baclofen Chinese alias and chlorophenol, BeiKangFen, becquerel Finn, lines and road, the road, chlorobenzene ammonia butyric acid, butyric acid chlorobenzene ammonia, and buck (gamma-aminobutyric acid analogues), for skeletal muscle relaxants. Mechanism is still unknown, may interfere with the excitatory neurotransmitter release, inhibition of synaptic transmission between the spinal cord. Baclofen activating GABA receptor beta, the lower spinal cord or polysynaptic reflex potential single synapses between and after spinal cord after root and root reflex potential, skeletal muscle relaxation effect, since the 70 s, has been widely used abroad in patients with spinal cord injury cramp, domestic use of these drugs have not been reported that this medicine has been the ministry of health license of the drug administration department agreed to the drug used in clinical.
Used to improve the pyramidal tract damage increased muscle tone of spasm symptoms, different causes of spastic hemiplegia and paraplegia, such as multiple sclerosis, cerebrovascular disease, spinal cord injury and myelitis sequela, children's cerebral palsy, tetanus, intractable hiccups; Improve Duchenne muscular dystrophy of duodenal obstruction in patients with recurrent vomiting; Ease the trigeminal neuralgia, neuralgia after herpes zoster, improve extrapyramidal after damage caused by myotonia such as Parkinson's disease, tardive dyskinesia, and Huntington chorea mild improvement. Reducing residual urine in patients with paraplegia after intravenous injection.
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