What is the Etomidate

Etomidate, attending functions, induction of general anesthesia (short-term anesthesia and pain relievers used).

Etomidate is a kind of hypnotic intravenous anesthetics, imidazoles derivatives, security, is one of commonly used drug anesthesia induction, etomidate has a history of 30 years of clinical application. Etomidate intravenous sedatives, is not the barbiturates are hydroxyl of imidazole salt, its structural formula as shown in the figure below, the formula for C14H16N2O2, molecular weight of 244.29. Etomidate insoluble in water, not stable in neutral solution.

Guidance: the pharmacological characteristics of etomidate is one of the important basis and clinical application of foundation: etomidate has sedative and hypnotic and forgotten, but no pain and muscle relaxant effect, is an important drug combination of general anesthesia sedatives. Etomidate effect is rapid, the body has a rapid metabolism and clear, CSHT study suggests after continuous infusion has no obvious accumulation in the body; Etomidate slightly to cycle suppression is its outstanding advantages, etomidate for breathing is affected, at the same time of reducing cerebral metabolic rate can reduce intracranial pressure, does not affect the cerebral perfusion pressure, etomidate emulsion injection can significantly reduce the pain and adverse reactions such as vascular injury, both for the clinical application provides a good background.